Референтни граници на БФАГ за Пулсативния индекс в пъпна артерия на плода (UA PI) в българската популация

П. Игнатов, З. Богословова, Т. Йорданова. (2024). Референтни граници на БФАГ за Пулсативния индекс в пъпна артерия на плода (UA PI) в българската популация. Фетална медицина, акушерство и гинекология. 1(8). doi: 10.70926/FMOG/1/2024.0002.UA.PI.1.8.

English abstract available

71cf53931935664bc6b610c 20241124130652690 info@orthogyn.com:bfog ignatov@orthogyn.com WEB-FORM Fetal Medicine, Obstetrics and Gynecology FMOG 30331250 10.70926/FMOG https://bfag.bg/journal 11 24 2024 1 10.70926/FMOG/1 https://bfag.bg/journal Bulgarian Federation of Obstetrics and Gynecology (BFOG) reference ranges for the Umbilical artery Pulsatility index (UA PI) Референтни граници на БФАГ за Пулсативния индекс в пъпна артерия на плода (UA PI) в българската популация Orthogyn Medical Center Petar Ignatov https://orcid.org/0000-0003-1656-5316 Teodora Yordanova-Ignatova https://orcid.org/0000-0003-0653-7370 Introduction: The assessment of fetal well-being is a key aspect of prenatal care. Doppler velocimetry of the umbilical artery (UA), particularly the Pulsatility Index (PI), is an established method for monitoring fetal hemodynamics. Accurate interpretation of the obtained values requires reference ranges specific to the population studied. The lack of such ranges for the Bulgarian population motivated our current research. Materials and Methods: Between 2022 and 2024, we conducted a prospective, observational, cross-sectional study involving 576 singleton low-risk pregnancies spanning the 28th and 40th gestational week. All pregnancies were dated using first-trimester ultrasound measurement of crown-rump length (CRL). Pregnancies with complications, fetal anomalies, or multiple gestations were excluded. Measurements of UA PI were performed by certified specialists following a standardized protocol. For each gestational week, the median, 5th, and 95th percentiles were calculated. Results: Based on the collected data, we developed reference ranges for UA PI, specific to the Bulgarian population. The results demonstrated a clear trend of decreasing with advancing gestation. This tendency corresponds to observations by other research groups; however, significant differences were noted in the numerical PI values for specific gestational weeks. In our cohort, the median and upper reference limit (50th and 95th percentiles) were comparable to that of the English population, but significantly lower than that reported for the Italian population. Conclusions: The use of well-defined reference ranges that accurately reflect local characteristics in placental blood flow dynamics is essential not only for the proper assessment of UA PI as an independent parameter, but also, for more precise calculation of the cerebroplacental ratio (CPR), which is a widely accepted marker for evaluating fetal condition in the third trimester of pregnancy. 11 24 2024 10.70926/FMOG/1/2024.0002.UA.PI.1.8 https://bfag.bg/2024/11/24/ua-pi

Референтни граници на БФАГ за Пулсативния индекс в пъпна артерия на плода (UA PI) в българската популация

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